high-performance liquid chromatography method for determination of 1-(2-phenylethyl)-5-(quinaldin-4-yl) biuret (a potential cytotoxic agent) in rat plasma
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منابع مشابه
development and validation of a high-performance liquid chromatography method with uv detection for determination of 1-(2-phenylethyl)-5- (quinaldin-4-yl) biuret in rat plasma
results under the above chromatography condition, biuret compound (peqb) and the internal standard were detected at 4.5 and 13.5 minutes, respectively. limit of quantitation of the peqb was 0.1 µg/ml. accuracy of the method over the concentration range of 0.1-100 µg/ml was between 88-109%. inter- and intraday precisions were 4-19% and 6-8%, respectively. a good relationship in the form of a pow...
متن کاملDevelopment and Validation of a High-Performance Liquid Chromatography Method With UV Detection for Determination of 1-(2-phenylethyl)-5- (quinaldin-4-yl) Biuret in Rat Plasma
BACKGROUND Recently, biuret derivatives have been reported as showing moderate to good cytotoxic effect against certain cancer cell lines. In this study, a high-performance liquid chromatography method was developed for determination of 1-(2-phenylethyl)-5-(quinaldin-4-yl) biuret (PEQB) in rat plasma to use in future studies on this compound and related derivatives. OBJECTIVES In this study, ...
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عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
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